The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

SureCN274906     4-(2-methylaminoethyl)phenol

Synonyms: AG-F-29859, CHEBI:17458, HMDB03633, ANW-58674, NSC-113958, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of WIN 5582


High impact information on WIN 5582


Biological context of WIN 5582

  • The nitrosation products of N-methyltyramine were p-hydroxy-m-nitro-N-nitroso-N-methyl-2-phenylethylamine and p-hydroxy-N-nitroso-N-methyl-2-phenylethylamine [5].

Gene context of WIN 5582


Analytical, diagnostic and therapeutic context of WIN 5582

  • The dose of NMT giving maximal gastrin-releasing activity was 25 microg/kg, and the 50% effective dose was approximately 10 microg/kg on oral administration to rats [6].


  1. Evidence that N-methyltyramine does not cause Phalaris aquatica-related sudden death in ruminants. Bourke, C., Colegate, S., Culvenor, R. Aust. Vet. J. (2006) [Pubmed]
  2. Analysis and prediction of absorption profile including hepatic first-pass metabolism of N-methyltyramine, a potent stimulant of gastrin release present in beer, after oral ingestion in rats by gastrointestinal-transit-absorption model. Kimura, T., Iwasaki, N., Yokoe, J.I., Haruta, S., Yokoo, Y., Ogawara, K.I., Higaki, K. Drug Metab. Dispos. (2000) [Pubmed]
  3. Cactus alkaloids XXXIII: beta-phenethylamines from the Guatemalan cactus Pilosocereus maxonii. Pummangura, S., Nichols, D.E., McLaughlin, J.L. Journal of pharmaceutical sciences. (1977) [Pubmed]
  4. Toxicity of Palicourea marcgravii: combined effects of fluoroacetate, N-methyltyramine and 2-methyltetrahydro-beta-carboline. Kemmerling, W. Z. Naturforsch., C, J. Biosci. (1996) [Pubmed]
  5. Nitrosation of N-methyltyramine and N-methyl-3-aminomethylindole, two barley malt alkaloids. Mangino, M.M., Libbey, L.M., Scanlan, R.A. IARC Sci. Publ. (1982) [Pubmed]
  6. Isolation from beer and structural determination of a potent stimulant of gastrin release. Yokoo, Y., Kohda, H., Kusumoto, A., Naoki, H., Matsumoto, N., Amachi, T., Suwa, Y., Fukazawa, H., Ishida, H., Tsuji, K., Nukaya, H. Alcohol Alcohol. (1999) [Pubmed]
WikiGenes - Universities