Chemical Compound Review:
AG-E-91561 2-(6,7,8,9-tetrahydro-5H- carbazol-3...
Synonyms:
NSC-117718, AC1L3YCF, AC1Q5VNL, CTK1A2634, NSC117718, ...
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Disease relevance of AH 2835
- It is noted that two cystic kidney diseases, the ocngenital nephrotic syndrome and infantile polycystic disease Potter type I are both inherited as autosomal recessive traits and are therefore likely to be caused by enzyme abnormalities, and that the compound AH 2835 can be used to produce experimental models of both of these diseases [1].
High impact information on AH 2835
- 5,6,7,8-tetrahydrocarbzzole-3-acetic acid (AH 2835) given to maternal rats throughout their gestation produces an experimental model of the autosomally inherited human infantile polycystic disease Potter type I in the rat foetuses [1].
References
- Polycystic disease of kidney, liver and pancreas; a possible patholgenesis. Mcgeoch, J.E., Darmady, E.M. J. Pathol. (1976) [Pubmed]
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