Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

PubChem12637 2,2-difluoroethanoic acid

Synonyms: AGN-PC-0D74FI, CHEMBL453969, AG-F-34488, ACMC-209iya, CHEBI:23716, ...

Commandeur, J.N. et al.

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High impact information on DIFLUOROACETIC ACID

Formation of DFAA and pyruvate could also be observed during in vitro metabolism of the cysteine conjugate of tetrafluoroethylene (TFE-CYS) by rat renal cytosol [1].

References

Nephrotoxicity of mercapturic acids of three structurally related 2,2-difluoroethylenes in the rat. Indications for different bioactivation mechanisms. Commandeur, J.N., Brakenhoff, J.P., De Kanter, F.J., Vermeulen, N.P. Biochem. Pharmacol. (1988) [Pubmed]

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