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Gene Review:

ccpA - catabolite control protein CcpA

Streptococcus mutans UA159

Wen, Z.T. et al., Simpson, C.L. et al.

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Disease relevance of ccpA

A locus containing a gene with homology to ccpA of other bacteria has been cloned from Streptococcus mutans LT11, sequenced, and named regM [1].

High impact information on ccpA

Deletion or mutation of a consensus catabolite response element alleviated glucose repression of fruA, but interestingly, inactivation of the ccpA gene had no discernible effect on catabolite repression of fruA [2].

References

Identification of a homolog of CcpA catabolite repressor protein in Streptococcus mutans. Simpson, C.L., Russell, R.R. Infect. Immun. (1998) [Pubmed]
Analysis of cis- and trans-acting factors involved in regulation of the Streptococcus mutans fructanase gene (fruA). Wen, Z.T., Burne, R.A. J. Bacteriol. (2002) [Pubmed]

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