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Gene Review

SPEG  -  SPEG complex locus

Homo sapiens

Synonyms: APEG-1, APEG1, Aortic preferentially expressed protein 1, BPEG, CNM5, ...
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Disease relevance of SPEG

  • This study examined whether the increased demand for pacemaker implants for carotid sinus syndrome (CSS) at the Regional Pacing Service in northeastern England was related to the establishment of a dedicated "syncope and falls" clinic or to the publication of NASPE and BPEG guidelines for pacing symptomatic bradycardia [1].

High impact information on SPEG


Anatomical context of SPEG


Analytical, diagnostic and therapeutic context of SPEG


  1. The impact of a dedicated "syncope and falls" clinic on pacing practice in northeastern England. Dey, A.B., Bexton, R.S., Tyman, M.M., Charles, R.G., Kenny, R.A. Pacing and clinical electrophysiology : PACE. (1997) [Pubmed]
  2. Genomic cloning and promoter analysis of aortic preferentially expressed gene-1. Identification of a vascular smooth muscle-specific promoter mediated by an E box motif. Hsieh, C.M., Yet, S.F., Layne, M.D., Watanabe, M., Hong, A.M., Perrella, M.A., Lee, M.E. J. Biol. Chem. (1999) [Pubmed]
  3. Obscurin-like 1, OBSL1, is a novel cytoskeletal protein related to obscurin. Geisler, S.B., Robinson, D., Hauringa, M., Raeker, M.O., Borisov, A.B., Westfall, M.V., Russell, M.W. Genomics (2007) [Pubmed]
  4. Percutaneous endoscopic gastrostomy placement without a skin incision: results of a prospective pilot study. Sedlack, R., Pochron, N., Baron, T. J. Clin. Gastroenterol. (2003) [Pubmed]
  5. X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1). Manjasetty, B.A., Niesen, F.H., Scheich, C., Roske, Y., Goetz, F., Behlke, J., Sievert, V., Heinemann, U., Büssow, K. BMC Struct. Biol. (2005) [Pubmed]
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