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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Idd14  -  insulin dependent diabetes susceptibility 14

Mus musculus

 
 
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High impact information on Idd14

  • In particular, we noted that diabetic backcross progeny, derived from NOD and C57BL/6 (B6) mouse strains, demonstrated increased heterozygousity for an interval encompassing Idd14 on chromosome 13 [1].
  • Dominant traits, detectable only in the F2 cross, were encoded by Chr 4 (Idd9) and two newly mapped loci on Chr 13 (Idd14) and 5 (Idd15) [2].

References

  1. A susceptibility allele from a non-diabetes-prone mouse strain accelerates diabetes in NOD congenic mice. Brodnicki, T.C., Quirk, F., Morahan, G. Diabetes (2003) [Pubmed]
  2. Crosses of NOD mice with the related NON strain. A polygenic model for IDDM. McAleer, M.A., Reifsnyder, P., Palmer, S.M., Prochazka, M., Love, J.M., Copeman, J.B., Powell, E.E., Rodrigues, N.R., Prins, J.B., Serreze, D.V. Diabetes (1995) [Pubmed]
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