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Gene Review

Arp  -  Arp lymphoid/erythroid hyperplasia

Mus musculus

 
 
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High impact information on Arp

  • There were 3 repeated sequences consisting of 42 residues that were highly homologous to those of protein Arp, an IgA-binding streptococcal cell wall protein, and streptococcal M6 and M24 proteins [1].
  • Association of the lymphoproliferative disease inducer gene Arp with autoimmunity and resistance to tumour growth [2].
  • Alloimmune interactions of a lymphoproliferative disease-inducer gene Arp and linkage to Pep-7 [3].
  • The Arp locus controls a range of alloimmune interactions between Arp incompatible lymphocytes [3].
  • There was no significant response in the NHPs to recombinant OspA or to Arp, a 37-kDa protein that elicits an antibody response during infection in mice [4].
 

Analytical, diagnostic and therapeutic context of Arp

  • The anti-tumour response generated by Arp-incompatible immunizations resulted in increased resistance to challenge with syngeneic tumour cells and in some cases total suppression of tumour growth [2].

References

  1. The gene sequence and some properties of protein H. A novel IgG-binding protein. Gomi, H., Hozumi, T., Hattori, S., Tagawa, C., Kishimoto, F., Björck, L. J. Immunol. (1990) [Pubmed]
  2. Association of the lymphoproliferative disease inducer gene Arp with autoimmunity and resistance to tumour growth. Matossian-Rogers, A. Clin. Exp. Immunol. (1985) [Pubmed]
  3. Alloimmune interactions of a lymphoproliferative disease-inducer gene Arp and linkage to Pep-7. Matossian-Rogers, A., DeGiorgi, L., Povey, S. Immunogenetics (1983) [Pubmed]
  4. Humoral immune response associated with lyme borreliosis in nonhuman primates: analysis by immunoblotting and enzyme-linked immunosorbent assay with sonicates or recombinant proteins. Pachner, A.R., Dail, D., Li, L., Gurey, L., Feng, S., Hodzic, E., Barthold, S. Clin. Diagn. Lab. Immunol. (2002) [Pubmed]
 
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