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Gene Review

rbcS  -  ribulose 1,5-bisphosphate...

Nostoc sp. PCC 7120

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Disease relevance of rbcS

  • The Anabaena rbcS gene is 61% homologous at the amino acid level with the gene from the unicellular cyanobacterium Anacystis and 37-38% homologous with the corresponding nuclear genes from eukaryotes [1].
  • The Rubisco activase (rca) gene is located downstream from rbcS in Anabaena sp. strain CA and is detected in other Anabaena/Nostoc strains [2].

High impact information on rbcS

  • To explore the role of individual residues in the small subunit of ribulose-1,5-bisphosphate carboxylase/oxygenase (EC, small subunits with single amino acid substitutions in three regions of relative sequence conservation were produced by directed mutagenesis of the rbcS gene from Anabaena 7120 [3].
  • In the filamentous cyanobacterium Anabaena, the gene for the small subunit (rbcS) of ribulose-1,5-bisphosphate carboxylase is linked to and transcribed together with the gene encoding the large subunit (rbcL) of the same enzyme [1].
  • The gene encoding ribulose 1,5-bisphosphate carboxylase/oxygenase (RubisCO) activase (rca) was uniformly localized downstream from the genes encoding the large and small subunits of RubisCO (rbcL and rbcS) in three strains of Anabaena species [4].

Chemical compound and disease context of rbcS


Biological context of rbcS

  • Two unknown open reading frames were shown to be located between rbcS and rca in strain CA and all the genes, rbcLrbcS, ORF1, ORF2, and rca were in the same transcriptional orientation [2].


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