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Gene Review:

Emv26 - endogenous ecotropic MuLV 26

Mus musculus

Synonyms: C58v-1, Emv-26

Taylor, B.A. et al., Fredrickson, T.N. et al.

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Disease relevance of Emv26

Another C58/J provirus was mapped to chromosome 8 and proved to be identical to the previously mapped C58v-1 virus inducibility gene of strain C58/Lw [1].

High impact information on Emv26

The 8.8-kilobase proviral DNA contained a 1.0-kilobase p21 ras coding segment which replaced most of the gp70-encoding portion of an MuLV, most likely the endogenous C58v-1 ecotropic virus [2].

References

A mouse linkage testing stock possessing multiple copies of the endogenous ecotropic murine leukemia virus genome. Taylor, B.A., Rowe, L. Genomics (1989) [Pubmed]
Biologic and molecular characterization of two newly isolated ras-containing murine leukemia viruses. Fredrickson, T.N., O'Neill, R.R., Rutledge, R.A., Theodore, T.S., Martin, M.A., Ruscetti, S.K., Austin, J.B., Hartley, J.W. J. Virol. (1987) [Pubmed]

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