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Gene Review

gumH  -  GumH protein

Xylella fastidiosa Temecula1

 
 
 
 
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Disease relevance of gumH

  • Overexpression, purification, biochemical characterization, and molecular modeling of recombinant GDP-mannosyltransferase (GumH) from Xylella fastidiosa [1].
 

High impact information on gumH

  • The GumH enzyme from Xylella fastidiosa catalyzes the transfer reaction of a mannose from GDP-mannose to the carrier lipid cellobiose-pyrophosphate-polyprenol (Glc(2)-PP-Lip), an intermediary in the reaction for the synthesis of the exopolysaccharide (EPS) fastidian gum [1].

References

  1. Overexpression, purification, biochemical characterization, and molecular modeling of recombinant GDP-mannosyltransferase (GumH) from Xylella fastidiosa. Muniz, J.R., Alves, C.A., de Pieri, C., Beltramini, L.M., Selistre-de-Araújo, H.S., Vettore, A.L., da Silva, F.R., Arruda, P., Garratt, R.C., Oliva, G., Souza, D.H. Biochem. Biophys. Res. Commun. (2004) [Pubmed]
 
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