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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

norD  -  norD protein

Brucella suis 1330

 
 
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Disease relevance of norD

  • A mutant of Brucella suis bearing a Tn5 insertion in norD, the last gene of the operon norEFCBQD, encoding nitric oxide reductase, was unable to survive under anaerobic denitrifying conditions [1].
 

High impact information on norD

 

Anatomical context of norD

  • The norD strain exhibited attenuated multiplication within nitric oxide-producing murine macrophages and rapid elimination in mice, hence demonstrating that norD is essential for Brucella virulence [1].

References

  1. Requirement of norD for Brucella suis virulence in a murine model of in vitro and in vivo infection. Loisel-Meyer, S., Jiménez de Bagüés, M.P., Bassères, E., Dornand, J., Köhler, S., Liautard, J.P., Jubier-Maurin, V. Infect. Immun. (2006) [Pubmed]
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