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Gene Review:

lcrE - secretion control protein

Yersinia pestis CO92

Viitanen, A.M. et al., Plano, G.V. et al.

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Disease relevance of lcrE

The lcrE gene is part of an operon in the lcr region of Yersinia enterocolitica O:3 [1].

High impact information on lcrE

These results indicated that a functional LCR secretion system was necessary for high-level expression of LCR stimulon proteins in the lcrE and lcrG mutants but not in an lcrH::cat mutant [2].
Transcription of the lcrE-containing operon and the adjacent lcrB locus was found to be divergent, and the corresponding transcripts overlapped about 1,200 nucleotides [1].

References

The lcrE gene is part of an operon in the lcr region of Yersinia enterocolitica O:3. Viitanen, A.M., Toivanen, P., Skurnik, M. J. Bacteriol. (1990) [Pubmed]
Mutations in yscC, yscD, and yscG prevent high-level expression and secretion of V antigen and Yops in Yersinia pestis. Plano, G.V., Straley, S.C. J. Bacteriol. (1995) [Pubmed]

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