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FRA10AC1  -  fragile site, folic acid type, rare,...

Homo sapiens

Synonyms: C10orf4, F26C11.1-like, FRA10A, PRO2972, Protein FRA10AC1
 
 
 
 
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High impact information on C10orf4

  • Folate-sensitive fragile site FRA10A is due to an expansion of a CGG repeat in a novel gene, FRA10AC1, encoding a nuclear protein [1].
 

Biological context of C10orf4

  • The FRA10AC1 gene consists of 19 exons and is transcribed in the centromeric direction from the FRA10A repeat [1].
 

Analytical, diagnostic and therapeutic context of C10orf4

  • Immunofluorescence analysis of full-length, recombinant EGFP-tagged FRA10AC1 protein showed that it was present exclusively in the nucleoplasm [1].

References

  1. Folate-sensitive fragile site FRA10A is due to an expansion of a CGG repeat in a novel gene, FRA10AC1, encoding a nuclear protein. Sarafidou, T., Kahl, C., Martinez-Garay, I., Mangelsdorf, M., Gesk, S., Baker, E., Kokkinaki, M., Talley, P., Maltby, E.L., French, L., Harder, L., Hinzmann, B., Nobile, C., Richkind, K., Finnis, M., Deloukas, P., Sutherland, G.R., Kutsche, K., Moschonas, N.K., Siebert, R., Gécz, J. Genomics (2004) [Pubmed]
 
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