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Gene Review

SFXN4  -  sideroflexin 4

Homo sapiens

Synonyms: BCRM1, Breast cancer resistance marker 1, COXPD18, Sideroflexin-4
 
 
 
 
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High impact information on SFXN4

  • According to the search of the human genome database, SFXN4 gene is mapped to chromosome 10q25-26 and spans more than 24.7kb of the genomic DNA [1].
  • During the large-scale sequencing analysis of a human fetal brain cDNA library, we isolated a cDNA encoding a novel sideroflexin protein (SFXN4), which showed 59% identity and 71% similarity to mouse sideroflexin4 [1].
 

Analytical, diagnostic and therapeutic context of SFXN4

  • RT-PCR result shows that the SFXN4 gene is expressed in many tissues [1].

References

  1. Molecular cloning and characterization of a novel human putative transmembrane protein homologous to mouse sideroflexin associated with sideroblastic anemia. Zheng, H., Ji, C., Zou, X., Wu, M., Jin, Z., Yin, G., Li, J., Feng, C., Cheng, H., Gu, S., Xie, Y., Mao, Y. DNA Seq. (2003) [Pubmed]
 
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