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Gene Review

Bmp10  -  bone morphogenetic protein 10

Mus musculus

Synonyms: BMP-10, Bone morphogenetic protein 10
 
 
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High impact information on Bmp10

  • Our data suggest an important pathway that involves a genetic interaction between BMP10, cell cycle regulatory proteins and several major cardiac transcription factors in orchestrating this transition in cardiogenesis at mid-gestation [1].
  • Overexpression of bone morphogenetic protein 10 in myocardium disrupts cardiac postnatal hypertrophic growth [2].

References

  1. BMP10 is essential for maintaining cardiac growth during murine cardiogenesis. Chen, H., Shi, S., Acosta, L., Li, W., Lu, J., Bao, S., Chen, Z., Yang, Z., Schneider, M.D., Chien, K.R., Conway, S.J., Yoder, M.C., Haneline, L.S., Franco, D., Shou, W. Development (2004) [Pubmed]
  2. Overexpression of bone morphogenetic protein 10 in myocardium disrupts cardiac postnatal hypertrophic growth. Chen, H., Yong, W., Ren, S., Shen, W., He, Y., Cox, K.A., Zhu, W., Li, W., Soonpaa, M., Payne, R.M., Franco, D., Field, L.J., Rosen, V., Wang, Y., Shou, W. J. Biol. Chem. (2006) [Pubmed]
 
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