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Gene Review:

yopD - translocator YopD

Yersinia enterocolitica W22703

Williams, A.W. et al., Wattiau, P. et al., Iriarte, M. et al., Håkansson, S. et al.

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High impact information on yopD

TyeA was found to interact with the translocator YopD and with residues 242-293 of YopN [1].
We also engineered a mutation in lcrH, the gene upstream from yopB and yopD, known to encode a 19-kDa acidic protein [2].
We conclude that the V-antigen operon ends with the yopD gene [3].
In this study, we constructed a yopD mutation in both wild-type and secretion-defective (ysc) Y. pestis to determine if the lcrH phenotype could be attributed to the decreased stability of YopD [4].

References

TyeA, a protein involved in control of Yop release and in translocation of Yersinia Yop effectors. Iriarte, M., Sory, M.P., Boland, A., Boyd, A.P., Mills, S.D., Lambermont, I., Cornelis, G.R. EMBO J. (1998) [Pubmed]
Individual chaperones required for Yop secretion by Yersinia. Wattiau, P., Bernier, B., Deslée, P., Michiels, T., Cornelis, G.R. Proc. Natl. Acad. Sci. U.S.A. (1994) [Pubmed]
YopB and YopD constitute a novel class of Yersinia Yop proteins. Håkansson, S., Bergman, T., Vanooteghem, J.C., Cornelis, G., Wolf-Watz, H. Infect. Immun. (1993) [Pubmed]
YopD of Yersinia pestis plays a role in negative regulation of the low-calcium response in addition to its role in translocation of Yops. Williams, A.W., Straley, S.C. J. Bacteriol. (1998) [Pubmed]

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