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Gene Review

rfbJ  -  CDP-abequose synthase

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

 
 
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Disease relevance of rfbJ

  • A 7.5 kb KpnI-generated fragment, from within the rfb cluster of Salmonella typhimurium LT2 that encodes abequose synthase (the rfbJ gene) which is necessary for O4 antigen synthesis, and flanking sequences, was inserted into a suicide vector [1].
 

High impact information on rfbJ

  • Analysis of the G + C ratio of the rfb cluster extended the area of low-G + C composition previously found in the sequence of rfbJ to the whole rfb gene cluster [2].

References

  1. Construction and characterization of isogenic O-antigen variants of Salmonella typhi. Hone, D.M., Harris, A.M., Lim, V., Levine, M.M. Mol. Microbiol. (1994) [Pubmed]
  2. Structure and sequence of the rfb (O antigen) gene cluster of Salmonella serovar typhimurium (strain LT2). Jiang, X.M., Neal, B., Santiago, F., Lee, S.J., Romana, L.K., Reeves, P.R. Mol. Microbiol. (1991) [Pubmed]
 
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