Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

rpoE - ECF RNA polymerase sigma factor RpoE

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Beck, B.J. et al., Kenyon, W.J. et al., Becker, L.A. et al., Skovierova, H. et al.

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Disease relevance of rpoE

Compensatory role of PspA, a member of the phage shock protein operon, in rpoE mutant Salmonella enterica serovar Typhimurium [1].

High impact information on rpoE

Using fluorescence ratio imaging, differences were observed in the Deltapsi of wild-type and rpoE or pspA mutant bacteria [1].
The role of RseC in thiamine synthesis was independent of rpoE [2].
An rpoE mutant strain was significantly impaired in both long-term C-starvation survival (LT-CSS) and in CSI cross-resistance to challenges with 20 mM H(2)O(2) for 40 min, 55 degrees C for 16 min, pH 3.1 for 60 min and 870.2 USP U polymyxin B ml(-1) (PmB) for 60 min, to varying degrees [3].
Comparison of the promoters revealed a consensus sequence almost identical to the sigma(E)-dependent rpoEp3 promoter directing expression of rpoE [4].

Chemical compound and disease context of rpoE

Evidence that rseC, a gene in the rpoE cluster, has a role in thiamine synthesis in Salmonella typhimurium [2].

References

Compensatory role of PspA, a member of the phage shock protein operon, in rpoE mutant Salmonella enterica serovar Typhimurium. Becker, L.A., Bang, I.S., Crouch, M.L., Fang, F.C. Mol. Microbiol. (2005) [Pubmed]
Evidence that rseC, a gene in the rpoE cluster, has a role in thiamine synthesis in Salmonella typhimurium. Beck, B.J., Connolly, L.E., De Las Peñas, A., Downs, D.M. J. Bacteriol. (1997) [Pubmed]
The starvation-stress response of Salmonella enterica serovar Typhimurium requires sigma(E)-, but not CpxR-regulated extracytoplasmic functions. Kenyon, W.J., Sayers, D.G., Humphreys, S., Roberts, M., Spector, M.P. Microbiology (Reading, Engl.) (2002) [Pubmed]
Characterization of the sigmaE-dependent rpoEp3 promoter of Salmonella enterica serovar Typhimurium. Skovierova, H., Rezuchova, B., Homerova, D., Roberts, M., Kormanec, J. FEMS Microbiol. Lett. (2006) [Pubmed]

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