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Gene Review

traY  -  component of oriT-specific nickase

Shigella flexneri 2b

 
 
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High impact information on traY

  • Site- and strand-specific nicking in vitro at oriT by the traY-traI endonuclease of plasmid R100 [1].
  • We show here that traY positively regulates R100-1 traM transcription, as has been found for F [2].
  • The traY protein from R1-19 was 44 residues shorter than the traY product from plasmid F, but there was some homology within the C-terminal halves of the traY gene products [3].
 

Biological context of traY

  • This supports the idea that the protein products of two genes, traY and traI, constitute an endonuclease that introduces a specific nick in vivo in the oriT region of the conjugative plasmids related to R100 [1].

References

 
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