High impact information on Cnih

• Transcripts of Cnih are highly abundant in the full grown oocyte and the ovulated unfertilized egg, while Cnil message is only detectable after activation of the embryonic genome at the eight-cell stage [1].
• In situ hybridization shows specific localization of Cnih transcripts to ovarian oocytes [1].

Biological context of Cnih

• Cnih encodes an open reading frame (ORF) of 144 amino acids that is 93% homologous (68% identical) to the Drosophila protein, whereas the ORF of Cnil contains two extra polypeptide regions not found in these other proteins [1].
• The lack of cytoplasmic polyadenylation of the maternally inherited Cnih transcript suggests that Cnih mRNA is translated in the full grown oocyte before, but not after, ovulation [1].

References