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Gene Review

Reep5  -  receptor accessory protein 5

Mus musculus

Synonyms: AI324241, AU022809, AW495741, DP1/TB2, Dp1, ...
 
 
 
 
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High impact information on Reep5

  • In stark contrast to the milder phenotypes that result from inactivation of E2Fs, we report that loss of Dp1 leads to death in utero because of the failure of extra-embryonic development [1].
  • Loss of Dp1 compromises the trophectoderm-derived tissues - specifically, the expansion of the ectoplacental cone and chorion, and endoreduplication in trophoblast giant cells [1].

References

  1. Dp1 is required for extra-embryonic development. Kohn, M.J., Bronson, R.T., Harlow, E., Dyson, N.J., Yamasaki, L. Development (2003) [Pubmed]
 
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