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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Epn1  -  epsin 1

Mus musculus

Synonyms: AA269831, EPS-15-interacting protein 1, Epsin-1, Ibp1, Intersectin-EH-binding protein 1
 
 
 
 
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High impact information on Epn1

  • The functional significance of these interactions was evaluated in a Xenopus oocyte expression system where co-expression of epsin and ENaC resulted in a down-regulation of ENaC activity; conversely, co-expression of epsin sub-domains acted as dominant-negative effectors and stimulated ENaC activity [1].
  • Clathrin-mediated endocytosis of the epithelial sodium channel. Role of epsin [1].

References

  1. Clathrin-mediated endocytosis of the epithelial sodium channel. Role of epsin. Wang, H., Traub, L.M., Weixel, K.M., Hawryluk, M.J., Shah, N., Edinger, R.S., Perry, C.J., Kester, L., Butterworth, M.B., Peters, K.W., Kleyman, T.R., Frizzell, R.A., Johnson, J.P. J. Biol. Chem. (2006) [Pubmed]
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