Gene Review:
Gas2 - growth arrest specific 2
Mus musculus
Synonyms:
GAS-2, Gas-2, Growth arrest-specific protein 2
- The death substrate Gas2 binds m-calpain and increases susceptibility to p53-dependent apoptosis. Benetti, R., Del Sal, G., Monte, M., Paroni, G., Brancolini, C., Schneider, C. EMBO J. (2001)
- Microtubule actin cross-linking factor (MACF): a hybrid of dystonin and dystrophin that can interact with the actin and microtubule cytoskeletons. Leung, C.L., Sun, D., Zheng, M., Knowles, D.R., Liem, R.K. J. Cell Biol. (1999)
- Microfilament reorganization during apoptosis: the role of Gas2, a possible substrate for ICE-like proteases. Brancolini, C., Benedetti, M., Schneider, C. EMBO J. (1995)
- Gas2, a growth arrest-specific protein, is a component of the microfilament network system. Brancolini, C., Bottega, S., Schneider, C. J. Cell Biol. (1992)
- Caspase-3 and caspase-7 but not caspase-6 cleave Gas2 in vitro: implications for microfilament reorganization during apoptosis. Sgorbissa, A., Benetti, R., Marzinotto, S., Schneider, C., Brancolini, C. J. Cell. Sci. (1999)
- gas2 is a multifunctional gene involved in the regulation of apoptosis and chondrogenesis in the developing mouse limb. Lee, K.K., Tang, M.K., Yew, D.T., Chow, P.H., Yee, S.P., Schneider, C., Brancolini, C. Dev. Biol. (1999)
- Phosphorylation of the growth arrest-specific protein Gas2 is coupled to actin rearrangements during Go-->G1 transition in NIH 3T3 cells. Brancolini, C., Schneider, C. J. Cell Biol. (1994)
- Effects of nutrient deprivation and differentiation on the expression of growth-arrest genes (gas and gadd) in F9 embryonal carcinoma cells. Fleming, J.V., Hay, S.M., Harries, D.N., Rees, W.D. Biochem. J. (1998)
- Dexamethasone signaling is required to establish the postmitotic state of adipocyte development. Shugart, E.C., Umek, R.M. Cell Growth Differ. (1997)
- Expression of growth arrest-specific (Gas) genes in murine keratinocytes: Gas2 is specifically regulated. Manzow, S., Brancolini, C., Marks, F., Richter, K.H. Exp. Cell Res. (1996)