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Gene Review:

gr - grizzled

Mus musculus

Kapfhamer, D. et al., Smoyer, W.E. et al., Qiao, X. et al.

Qiao, Pennesi, Seong, Gao, Burmeister, Wu,

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High impact information on gr

Thus, genetic mapping of the gr locus will also yield information about the mh location [1].
In 539 progeny tested, we found no recombination between the gr gene, the gene for anti-Muellerian hormone (Amh), and the microsatellite markers D10Mit7, D10Mit21, and D10Mit23 [1].
The region linked to grizzled is homologous to a gene-rich region on human Chromosome 19p13.3 [1].
This disease is inherited in an autosomal recessive manner, with complete penetrance, and has been linked to grizzled and waltzer on mouse chromosome 10 [2].

Anatomical context of gr

Photoreceptor degeneration and rd1 mutation in the grizzled/mocha mouse strain [3].

References

Genetic map of the region around grizzled (gr) and mocha (mh) on mouse chromosome 10, homologous to human 19p13.3. Kapfhamer, D., Burmeister, M. Genomics (1994) [Pubmed]
Inherited interstitial nephritis in kdkd mice. Smoyer, W.E., Kelly, C.J. Int. Rev. Immunol. (1994) [Pubmed]
Photoreceptor degeneration and rd1 mutation in the grizzled/mocha mouse strain. Qiao, X., Pennesi, M., Seong, E., Gao, H., Burmeister, M., Wu, S.M. Vision Res. (2003) [Pubmed]

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