Gene Review:
E120R - structural protein p14.5
African swine fever virus
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Disease relevance of E120R
- The E120R gene product has been expressed in Escherichia coli, purified, and used as an antigen for antibody production [1].
- The gene encoding the structural protein p14.5 of African swine fever virus (ASFV) has been mapped and sequenced [1].
High impact information on E120R
- This gene, designated E120R, is located in the Sa/l H/EcoRl E restriction fragment of the ASFV genome and is predicted to encode a protein of 120 amino acids with a molecular weight of 13.4 kDa [1].
- Characterization of the African swine fever virus structural protein p14.5: a DNA binding protein [1].
Analytical, diagnostic and therapeutic context of E120R
- Northern-blot analysis showed that E120R is transcribed at late times during the viral replication cycle [1].
References
- Characterization of the African swine fever virus structural protein p14.5: a DNA binding protein. Martinez-Pomares, L., Simon-Mateo, C., Lopez-Otin, C., Viñuela, E. Virology (1997) [Pubmed]
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