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DGKH  -  diacylglycerol kinase, eta

Homo sapiens

Synonyms: DAG kinase eta, DGK-eta, DGKeta, Diacylglycerol kinase eta, Diglyceride kinase eta
 
 
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High impact information on DGKH

  • The expression patterns, subcellular distribution, and regulatory mechanisms of DGK kappa are distinct from those of DGKdelta and DGKeta despite high structural similarity, suggesting unique functions of the individual type II isozymes [1].
  • The tissue distribution of DGKeta message (determined by ribonuclease protection assays) and protein (determined by immunoblots) was broader than reported for other DGKs, indicating that DGKeta may play a more general role in regulating cellular DG levels than other DGKs [2].
  • Of the 3 genes residing within the MRA, Receptor Activator of NK-kappa-B Ligand (RANKL) and Diacylglycerol Kinase (DGKH) showed no change in expression levels in tumors compared to normal tissue [3].
  • Therefore in 2001 the German Society of Hospital Hygiene (DGKH) specified its requirements and recommendations for determining cleaning efficacy separately from those for disinfection [4].
  • Recommendations for surgical hand disinfection -- requirements, implementation and need for research. A proposal by representatives of the SFHH, DGHM and DGKH for a European discussion [5].

References

  1. Identification and characterization of a novel human type II diacylglycerol kinase, DGK kappa. Imai, S., Kai, M., Yasuda, S., Kanoh, H., Sakane, F. J. Biol. Chem. (2005) [Pubmed]
  2. Cloning and characterization of a glucocorticoid-induced diacylglycerol kinase. Klauck, T.M., Xu, X., Mousseau, B., Jaken, S. J. Biol. Chem. (1996) [Pubmed]
  3. Alteration of AKAP220, an upstream component of the Rb pathway, in oral carcinogenesis. Garnis, C., Rosin, M.P., Zhang, L., Lam, W.L. Int. J. Cancer (2005) [Pubmed]
  4. The importance of cleaning for the overall results of processing endoscopes. Martiny, H., Floss, H., Zühlsdorf, B. J. Hosp. Infect. (2004) [Pubmed]
  5. Recommendations for surgical hand disinfection -- requirements, implementation and need for research. A proposal by representatives of the SFHH, DGHM and DGKH for a European discussion. Labadie, J.C., Kampf, G., Lejeune, B., Exner, M., Cottron, O., Girard, R., Orlick, M., Goetz, M.L., Darbord, J.C., Kramer, A. J. Hosp. Infect. (2002) [Pubmed]
 
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