Gene Review:
Irf2 - interferon regulatory factor 2
Mus musculus
Synonyms:
9830146E22Rik, AI646973, IRF-2, Interferon regulatory factor 2, Irf-2
- Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis. Fehr, T., Schoedon, G., Odermatt, B., Holtschke, T., Schneemann, M., Bachmann, M.F., Mak, T.W., Horak, I., Zinkernagel, R.M. J. Exp. Med. (1997)
- Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development. Matsuyama, T., Kimura, T., Kitagawa, M., Pfeffer, K., Kawakami, T., Watanabe, N., Kündig, T.M., Amakawa, R., Kishihara, K., Wakeham, A. Cell (1993)
- Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cells. Lohoff, M., Duncan, G.S., Ferrick, D., Mittrücker, H.W., Bischof, S., Prechtl, S., Röllinghoff, M., Schmitt, E., Pahl, A., Mak, T.W. J. Exp. Med. (2000)
- Susceptibility of IFN regulatory factor-1 and IFN consensus sequence binding protein-deficient mice to brucellosis. Ko, J., Gendron-Fitzpatrick, A., Splitter, G.A. J. Immunol. (2002)
- Characterization of the DNA binding domain of the mouse IRF-2 protein. Uegaki, K., Shirakawa, M., Fujita, T., Taniguchi, T., Kyogoku, Y. Protein Eng. (1993)
- Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1. Tanaka, N., Ishihara, M., Kitagawa, M., Harada, H., Kimura, T., Matsuyama, T., Lamphier, M.S., Aizawa, S., Mak, T.W., Taniguchi, T. Cell (1994)
- CD8(+) T cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-alpha/beta signaling. Hida, S., Ogasawara, K., Sato, K., Abe, M., Takayanagi, H., Yokochi, T., Sato, T., Hirose, S., Shirai, T., Taki, S., Taniguchi, T. Immunity (2000)
- Gene repression by coactivator repulsion. Senger, K., Merika, M., Agalioti, T., Yie, J., Escalante, C.R., Chen, G., Aggarwal, A.K., Thanos, D. Mol. Cell (2000)
- The growth-dependent expression of angiotensin II type 2 receptor is regulated by transcription factors interferon regulatory factor-1 and -2. Horiuchi, M., Koike, G., Yamada, T., Mukoyama, M., Nakajima, M., Dzau, V.J. J. Biol. Chem. (1995)
- IRF-2 is involved in up-regulation of nonmuscle myosin heavy chain II-A gene expression during phorbol ester-induced promyelocytic HL-60 differentiation. Chung, M.C., Kawamoto, S. J. Biol. Chem. (2004)
- Interferon regulatory transcription factors are constitutively expressed and spatially regulated in the mouse lens. Li, W., Nagineni, C.N., Efiok, B., Chepelinsky, A.B., Egwuagu, C.E. Dev. Biol. (1999)
- The role of the interferon regulatory factors, IRF-1 and IRF-2, in LPS-induced cyclooxygenase-2 (COX-2) expression in vivo and in vitro. Zhang, S., Thomas, K., Blanco, J.C., Salkowski, C.A., Vogel, S.N. J. Endotoxin Res. (2002)
- Interferon regulatory factor-1 up-regulates angiotensin II type 2 receptor and induces apoptosis. Horiuchi, M., Yamada, T., Hayashida, W., Dzau, V.J. J. Biol. Chem. (1997)
- Forced expression of the interferon regulatory factor 2 oncoprotein causes polyploidy and cell death in FDC-P1 myeloid hematopoietic progenitor cells. Xie, R.L., van Wijnen, A.J., van der Meijden, C.M., Stein, J.L., Stein, G.S. Cancer Res. (2002)
- Differential dysregulation of nitric oxide production in macrophages with targeted disruptions in IFN regulatory factor-1 and -2 genes. Salkowski, C.A., Barber, S.A., Detore, G.R., Vogel, S.N. J. Immunol. (1996)
- Interferon regulatory factor-2 regulates cell growth through its acetylation. Masumi, A., Yamakawa, Y., Fukazawa, H., Ozato, K., Komuro, K. J. Biol. Chem. (2003)
- The oncogenic transcription factor IRF-2 possesses a transcriptional repression and a latent activation domain. Yamamoto, H., Lamphier, M.S., Fujita, T., Taniguchi, T., Harada, H. Oncogene (1994)
- IFN-gamma induces the kappa intron enhancer via an IFN-stimulated response element. Damore, M.A., Omori, S.A., Wall, R. J. Immunol. (1996)
- Interferon regulatory factor-2 is a transcriptional activator in muscle where It regulates expression of vascular cell adhesion molecule-1. Jesse, T.L., LaChance, R., Iademarco, M.F., Dean, D.C. J. Cell Biol. (1998)
- IL-12 is dysregulated in macrophages from IRF-1 and IRF-2 knockout mice. Salkowski, C.A., Kopydlowski, K., Blanco, J., Cody, M.J., McNally, R., Vogel, S.N. J. Immunol. (1999)
- Impaired class II transactivator expression in mice lacking interferon regulatory factor-2. Xi, H., Goodwin, B., Shepherd, A.T., Blanck, G. Oncogene (2001)
- Regulation of lipopolysaccharide sensitivity by IFN regulatory factor-2. Cuesta, N., Salkowski, C.A., Thomas, K.E., Vogel, S.N. J. Immunol. (2003)
- Negative control of basophil expansion by IRF-2 critical for the regulation of Th1/Th2 balance. Hida, S., Tadachi, M., Saito, T., Taki, S. Blood (2005)
- Characterization of a novel IRF-1-deficient mutant cell line. Lim, S.P., Hui, K.M. Immunogenetics (1994)