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Gene Review

cob  -  cytochrome b

Schizosaccharomyces pombe

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High impact information on cob

  • The DNA sequence of the cob region of the Schizosaccharomyces pombe mitochondrial DNA has been determined [1].
  • In addition to the potential intron folding, long helical structures involving repetitive sequences can be formed in the flanking cob exon regions [1].
  • As was seen for the Sch. pombe cox1 gene (Lang, 1984), the cob exons are translated using the universal genetic code and this distinguishes Sch. pombe mitochondria from all other fungal and animal mitochondrial systems [1].
  • The Sch. pombe cob intron has the potential of assuming an RNA secondary structure almost identical to that proposed for the first two cox1 introns (group II) in S. cerevisiae and the p1-cox1 intron in Podospora anserina [1].


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