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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

TXLNB  -  taxilin beta

Homo sapiens

Synonyms: Beta-taxilin, C6orf198, DKFZp451A175, LST001, MDP77, ...
 
 
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High impact information on TXLNB

  • Long-term effects of muscle-derived protein with molecular mass of 77 kDa (MDP77) on nerve regeneration [1].
  • Furthermore, histological and immunohistochemical evaluations suggested that MDP77 treatment accelerates Schwann cell migration, followed by enhanced maturation of regenerating axons, resulting in functional recovery of both the nerves and the atrophied, denervated muscle [1].
  • Electrophysiological measurements and the ratio of soleus muscle weight corroborated the positive effects of MDP77 on motor nerve regeneration, but no facilitation of sensory nerve recovery was observed [1].
  • Fourteen-millimeter bridge grafts of the right sciatic nerve of SD rats were carried out with silicone tubes containing a solution of type I collagen together with 0, 5, 10, or 20 microg/ml recombinant human MDP77 (N = 10 in each group) [1].
 

Biological context of TXLNB

References

  1. Long-term effects of muscle-derived protein with molecular mass of 77 kDa (MDP77) on nerve regeneration. Itoh, S., Fujimori, K.E., Uyeda, A., Matsuda, A., Kobayashi, H., Shinomiya, K., Tanaka, J., Taguchi, T. J. Neurosci. Res. (2005) [Pubmed]
  2. Muscle-specific protein MDP77 specifically promotes motor nerve regeneration in rats. Itoh, S., Uyeda, A., Hukuoka, Y., Fujimori, K.E., Matsuda, A., Ichinose, S., Kobayashi, H., Shinomiya, K., Tanaka, J., Taguchi, T. Neurosci. Lett. (2004) [Pubmed]
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