Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

Sv40is_mapped - SV40 viral integration site (mapped)

Rattus norvegicus

This record was discontinued.

Deppert, W. et al., Topp, W.C. et al., Petit, C.A. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Sv40is_mapped

Therefore, we suggest that metabolic stabilization of p53 during cellular transformation with SV40 is mediated by a cellular process and probably is the consequence of the large-T-induced transformed phenotype [1].
Immortalization of rodent embryo fibroblasts by SV40 is maintained by the A gene [2].
The small-t protein of SV40 is required for loss of actin cable networks and plasminogen activator synthesis in transformed rat cells [3].

References

Modulation of p53 protein expression during cellular transformation with simian virus 40. Deppert, W., Haug, M., Steinmayer, T. Mol. Cell. Biol. (1987) [Pubmed]
Immortalization of rodent embryo fibroblasts by SV40 is maintained by the A gene. Petit, C.A., Gardes, M., Feunteun, J. Virology (1983) [Pubmed]
The small-t protein of SV40 is required for loss of actin cable networks and plasminogen activator synthesis in transformed rat cells. Topp, W.C., Rifkin, D.B. Virology (1980) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share