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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

atp-2  -  Protein ATP-2

Caenorhabditis elegans

 
 
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High impact information on atp-2

  • We further show that atp-2, lov-1, and pkd-2 act in the same molecular pathway [1].
  • Surprisingly, the nuo-1 and atp-2 mutations significantly lengthen the life spans of the arrested animals [2].
  • The atp-2 gene encodes the active-site subunit of complex V, the ATP synthase [2].

References

  1. ATP-2 interacts with the PLAT domain of LOV-1 and is involved in Caenorhabditis elegans polycystin signaling. Hu, J., Barr, M.M. Mol. Biol. Cell (2005) [Pubmed]
  2. Mitochondrial respiratory chain deficiency in Caenorhabditis elegans results in developmental arrest and increased life span. Tsang, W.Y., Sayles, L.C., Grad, L.I., Pilgrim, D.B., Lemire, B.D. J. Biol. Chem. (2001) [Pubmed]
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