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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review

iff-1  -  Protein IFF-1

Caenorhabditis elegans

 
 
 
 
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Disease relevance of iff-1

  • On the other hand, iff-1 mRNA is expressed in the gonad, and the lack of iff-1 activity causes sterility with an underproliferated germline resulting from impaired mitotic proliferation in both hermaphrodites and males [1].
 

High impact information on iff-1

 

Biological context of iff-1

  • In spite of underproliferation, meiotic nuclei are observed, as revealed by presence of immunoreactivity to the anti-HIM-3 antibody; however, no gametogenesis occurs in the iff-1 gonads [1].

References

 
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