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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

mdf-2  -  Protein MDF-2

Caenorhabditis elegans

 
 
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High impact information on mdf-2

  • Here we show that mdf-1 and mdf-2 are components of the spindle-assembly checkpoint in Caenorhabditis elegans, and are essential for the long-term survival and fertility of this organism [1].
  • Reduction-of-function alleles of mdf-2 and mdf-3 suppress APC mutants and exhibit pleiotropic phenotypes in an otherwise wild-type background [2].

References

  1. Components of the spindle-assembly checkpoint are essential in Caenorhabditis elegans. Kitagawa, R., Rose, A.M. Nat. Cell Biol. (1999) [Pubmed]
  2. Components of the Spindle Assembly Checkpoint Regulate the Anaphase-Promoting Complex During Meiosis in Caenorhabditis elegans. Stein, K.K., Davis, E.S., Hays, T., Golden, A. Genetics (2007) [Pubmed]
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