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Gene Review

spe-27  -  Protein SPE-27

Caenorhabditis elegans

 
 
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High impact information on spe-27

  • To better understand this signal transduction pathway, we isolated suppressors of a mutation in the spe-27 gene, which is part of the pathway [1].
  • Mutations in three genes (spe-8, spe-12, and spe-27) prevent the initiation of this morphogenesis, termed activation [2].
  • Mutant alleles of spe-12, spe-27, and spe-29 exhibit genetic interactions that suggest that the wild-type products of these genes function in a common signaling pathway to initiate sperm activation [2].
  • Consistent with this model, when spe-27 mutant male spermatids without seminal fluid are artificially inseminated into hermaphrodites, they fail to activate [3].
  • Genetic and molecular analysis of spe-27, a gene required for spermiogenesis in Caenorhabditis elegans hermaphrodites [3].
 

Biological context of spe-27

 

Anatomical context of spe-27

References

 
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