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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Myo5b  -  myosin VB

Mus musculus

Synonyms: AI661750, Kiaa1119, Unconventional myosin-Vb, mKIAA1119
 
 
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High impact information on Myo5b

  • Systematic analysis of the mRNA and protein distribution of these myosins indicates that Myo5a is most abundant in brain, whereas Myo5b and Myo5c are expressed chiefly in non-neuronal tissues [1].
 

Anatomical context of Myo5b

  • Evidence is also presented that the globular tail of myosin-Va, but not myosin-Vb, targets this motor molecule to the centrosome as confirmed by colocalization in cells stained with antibodies to (gamma)-tubulin [2].

References

  1. Human myosin-Vc is a novel class V myosin expressed in epithelial cells. Rodriguez, O.C., Cheney, R.E. J. Cell. Sci. (2002) [Pubmed]
  2. Subcellular localization of GFP-myosin-V in live mouse melanocytes. Tsakraklides, V., Krogh, K., Wang, L., Bizario, J.C., Larson, R.E., Espreafico, E.M., Wolenski, J.S. J. Cell. Sci. (1999) [Pubmed]
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