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Gene Review:

nct - Nakano cataract

Mus musculus

This record was replaced with 12892.

Tripathi, B.J. et al., Hayashi, S. et al., Iida, F. et al., Hiai, H. et al.

Hiai, Kato, Horiuchi, Shimada, Tsuruyama, Watanabe, Matsuzawa,

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Disease relevance of nct

In mice, the models include the Cts strain, Fraser mouse, lens opacity gene (Lop) strain, Lop-2 and Lop-3 strains, Philly mouse, Nakano mouse, Nop strain, Deer mouse, Emory mouse, Swiss Webster strain, Balb/c-nct/nct mouse, and SAM-R/3 strain [1].
Spontaneous lymphomas from a strain of hereditary cataract (CAC-nct/+) mice were examined by light and electron microscopy and by immunohistochemical reaction for the mouse heavy and light immunoglobulin chains [2].

High impact information on nct

Mapping of Nakano cataract gene nct on mouse chromosome 16 [3].
Neither allelism nor linkage was found between rlc and nct, another recessive gene in Nakano cataract mice [4].

References

Rodent models of congenital and hereditary cataract in man. Tripathi, B.J., Tripathi, R.C., Borisuth, N.S., Dhaliwal, R., Dhaliwal, D. Lens and eye toxicity research. (1991) [Pubmed]
Spontaneous follicular center cell lymphomas of B cell origin in cataract mice. Hayashi, S., Nonoyama, T., Miyajima, H. Jpn. J. Cancer Res. (1992) [Pubmed]
Mapping of Nakano cataract gene nct on mouse chromosome 16. Hiai, H., Kato, S., Horiuchi, Y., Shimada, R., Tsuruyama, T., Watanabe, T., Matsuzawa, A. Genomics (1998) [Pubmed]
Rupture of lens cataract: a novel hereditary recessive cataract model in the mouse. Iida, F., Matsushima, Y., Hiai, H., Uga, S., Honda, Y. Exp. Eye Res. (1997) [Pubmed]

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