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Gene Review

jkk-1  -  Protein JKK-1

Caenorhabditis elegans

 
 
 
 
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High impact information on jkk-1

  • Both jnk-1 and jkk-1 are expressed in most neurons. jkk-1 null mutant animals exhibit defects in locomotion that can be rescued by the conditional expression of JKK-1 in mutant adults, suggesting that the defect is not due to a developmental error [1].

References

  1. A Caenorhabditis elegans JNK signal transduction pathway regulates coordinated movement via type-D GABAergic motor neurons. Kawasaki, M., Hisamoto, N., Iino, Y., Yamamoto, M., Ninomiya-Tsuji, J., Matsumoto, K. EMBO J. (1999) [Pubmed]
 
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