Gene Review:
Npm1 - nucleophosmin 1
Mus musculus
Synonyms:
B23, NO38, NPM, Npm, Nucleolar phosphoprotein B23, ...
- Nucleophosmin-anaplastic lymphoma kinase associated with anaplastic large-cell lymphoma activates the phosphatidylinositol 3-kinase/Akt antiapoptotic signaling pathway. Bai, R.Y., Ouyang, T., Miething, C., Morris, S.W., Peschel, C., Duyster, J. Blood (2000)
- Nucleophosmin is required for DNA integrity and p19Arf protein stability. Colombo, E., Bonetti, P., Lazzerini Denchi, E., Martinelli, P., Zamponi, R., Marine, J.C., Helin, K., Falini, B., Pelicci, P.G. Mol. Cell. Biol. (2005)
- DNA cloning and amino acid sequence determination of a major constituent protein of mammalian nucleoli. Correspondence of the nucleoplasmin-related protein NO38 to mammalian protein B23. Schmidt-Zachmann, M.S., Franke, W.W. Chromosoma (1988)
- Nucleophosmin: A versatile molecule associated with hematological malignancies. Naoe, T., Suzuki, T., Kiyoi, H., Urano, T. Cancer Sci. (2006)
- Nucleophosmin regulates cell cycle progression and stress response in hematopoietic stem/progenitor cells. Li, J., Sejas, D.P., Rani, R., Koretsky, T., Bagby, G.C., Pang, Q. J. Biol. Chem. (2006)
- Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase. Peter, M., Nakagawa, J., Dorée, M., Labbé, J.C., Nigg, E.A. Cell (1990)
- Cre-lox-regulated conditional RNA interference from transgenes. Ventura, A., Meissner, A., Dillon, C.P., McManus, M., Sharp, P.A., Van Parijs, L., Jaenisch, R., Jacks, T. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Role of nucleophosmin in embryonic development and tumorigenesis. Grisendi, S., Bernardi, R., Rossi, M., Cheng, K., Khandker, L., Manova, K., Pandolfi, P.P. Nature (2005)
- Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23. Bertwistle, D., Sugimoto, M., Sherr, C.J. Mol. Cell. Biol. (2004)
- Characterization of centrosomal association of nucleophosmin/B23 linked to Crm1 activity. Shinmura, K., Tarapore, P., Tokuyama, Y., George, K.R., Fukasawa, K. FEBS Lett. (2005)
- Increased stability of nucleophosmin/B23 in anti-apoptotic effect of ras during serum deprivation. Chou, C.C., Yung, B.Y. Mol. Pharmacol. (2001)
- Inducible and reversible suppression of Npm1 gene expression using stably integrated small interfering RNA vector in mouse embryonic stem cells. Wang, B.B., Lu, R., Wang, W.C., Jin, Y. Biochem. Biophys. Res. Commun. (2006)
- Nucleolar distribution of proteins B23 and nucleolin in mouse preimplantation embryos as visualized by immunoelectron microscopy. Biggiogera, M., Bürki, K., Kaufmann, S.H., Shaper, J.H., Gas, N., Amalric, F., Fakan, S. Development (1990)
- Distribution of nucleolar proteins B23 and nucleolin during mouse spermatogenesis. Biggiogera, M., Kaufmann, S.H., Shaper, J.H., Gas, N., Amalric, F., Fakan, S. Chromosoma (1991)
- MEK inhibition and phosphorylation of serine 4 on B23 are two coincident events in mitosis. Hayne, C., Xiang, X., Luo, Z. Biochem. Biophys. Res. Commun. (2004)
- B23 is a downstream target of polyamine-modulated CK2. Lawson, K., Larentowicz, L., Laury-Kleintop, L., Gilmour, S.K. Mol. Cell. Biochem. (2005)
- The oncogenic fusion protein nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) induces two distinct malignant phenotypes in a murine retroviral transplantation model. Miething, C., Grundler, R., Fend, F., Hoepfl, J., Mugler, C., von Schilling, C., Morris, S.W., Peschel, C., Duyster, J. Oncogene (2003)
- Nucleophosmin/B23-binding peptide inhibits tumor growth and up-regulates transcriptional activity of p53. Chan, H.J., Weng, J.J., Yung, B.Y. Biochem. Biophys. Res. Commun. (2005)
- A mammalian in vitro centriole duplication system: evidence for involvement of CDK2/cyclin E and nucleophosmin/B23 in centrosome duplication. Tarapore, P., Okuda, M., Fukasawa, K. Cell Cycle (2002)
- PARP-1 and PARP-2 interact with nucleophosmin/B23 and accumulate in transcriptionally active nucleoli. Meder, V.S., Boeglin, M., de Murcia, G., Schreiber, V. J. Cell. Sci. (2005)
- CD2 promoter regulated nucleophosmin-anaplastic lymphoma kinase in transgenic mice causes B lymphoid malignancy. Turner, S.D., Merz, H., Yeung, D., Alexander, D.R. Anticancer Res. (2006)
- Relief of YY1-induced transcriptional repression by protein-protein interaction with the nucleolar phosphoprotein B23. Inouye, C.J., Seto, E. J. Biol. Chem. (1994)
- In vivo and in vitro phosphorylation studies of numatrin, a cell cycle regulated nuclear protein, in insulin-stimulated NIH 3T3 HIR cells. Feuerstein, N., Randazzo, P.A. Exp. Cell Res. (1991)