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Gene Review

Olfr50  -  olfactory receptor 50

Mus musculus

Synonyms: GA_x6K02T2NLDC-33487752-33488690, ID3, MOR136-6, Mor136-6, Olfactory receptor 136-6, ...
 
 
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High impact information on Olfr50

  • The 14-kD domain can possibly form an additional part of the catalytic site as it harbors the epitope for the monoclonal antibody ID3 which inhibits enzymatic activity but not the formation of the ligase-tubulin complex [1].
  • The role of BMP signalling in the control of ID3 expression in the hair follicle [2].
  • ID3, a gene expressed in the dermal papilla of both vibrissa and pelage follicles, is a BMP target, and as such, we found that ID3 was expressed from the earliest stages of morphogenesis [2].

References

  1. Tubulin-tyrosine ligase has a binding site on beta-tubulin: a two-domain structure of the enzyme. Wehland, J., Weber, K. J. Cell Biol. (1987) [Pubmed]
  2. The role of BMP signalling in the control of ID3 expression in the hair follicle. O'Shaughnessy, R.F., Christiano, A.M., Jahoda, C.A. Exp. Dermatol. (2004) [Pubmed]
 
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