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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

vab-9  -  Protein VAB-9

Caenorhabditis elegans

 
 
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High impact information on vab-9

  • Mutations in vab-9 enhance adhesion defects through functional loss of the cell junction genes apical junction molecule 1 (ajm-1) and discs large 1 (dlg-1), suggesting that VAB-9 is involved in cell adhesion [1].
  • In vab-9 mutants, morphological defects correlate with disorganization of F-actin at the adherens junction; however, localization of the cadherin-catenin complex and epithelial polarity is normal [1].

References

  1. The cell junction protein VAB-9 regulates adhesion and epidermal morphology in C. elegans. Simske, J.S., Köppen, M., Sims, P., Hodgkin, J., Yonkof, A., Hardin, J. Nat. Cell Biol. (2003) [Pubmed]
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