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Gene Review

Skil  -  SKI-like

Mus musculus

Synonyms: 9130011J04Rik, Ski-like protein, Ski-related oncogene, Ski-related protein, Skir, ...
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Disease relevance of Skil


High impact information on Skil


Biological context of Skil


Anatomical context of Skil


Analytical, diagnostic and therapeutic context of Skil


  1. Ubiquitin-dependent degradation of SnoN and Ski is increased in renal fibrosis induced by obstructive injury. Fukasawa, H., Yamamoto, T., Togawa, A., Ohashi, N., Fujigaki, Y., Oda, T., Uchida, C., Kitagawa, K., Hattori, T., Suzuki, S., Kitagawa, M., Hishida, A. Kidney Int. (2006) [Pubmed]
  2. Gene expression profiling in two morphologically different uterine cervical carcinoma cell lines derived from a single donor using a human cancer cDNA array. Fujimoto, T., Nishikawa, A., Iwasaki, M., Akutagawa, N., Teramoto, M., Kudo, R. Gynecol. Oncol. (2004) [Pubmed]
  3. The sno gene, which encodes a component of the histone deacetylase complex, acts as a tumor suppressor in mice. Shinagawa, T., Dong, H.D., Xu, M., Maekawa, T., Ishii, S. EMBO J. (2000) [Pubmed]
  4. Defective T-cell activation is associated with augmented transforming growth factor Beta sensitivity in mice with mutations in the Sno gene. Pearson-White, S., McDuffie, M. Mol. Cell. Biol. (2003) [Pubmed]
  5. The ski/sno protooncogene family in hematopoietic development. Pearson-White, S., Deacon, D., Crittenden, R., Brady, G., Iscove, N., Quesenberry, P.J. Blood (1995) [Pubmed]
  6. Proto-oncogene Sno expression, alternative isoforms and immediate early serum response. Pearson-White, S., Crittenden, R. Nucleic Acids Res. (1997) [Pubmed]
  7. Up-regulated transcriptional repressors SnoN and Ski bind Smad proteins to antagonize transforming growth factor-beta signals during liver regeneration. Macias-Silva, M., Li, W., Leu, J.I., Crissey, M.A., Taub, R. J. Biol. Chem. (2002) [Pubmed]
  8. Downregulation of Smad transcriptional corepressors SnoN and Ski in the fibrotic kidney: an amplification mechanism for TGF-beta1 signaling. Yang, J., Zhang, X., Li, Y., Liu, Y. J. Am. Soc. Nephrol. (2003) [Pubmed]
  9. Cloning and characterization of the murine homolog of the sno proto-oncogene reveals a novel splice variant. Pelzer, T., Lyons, G.E., Kim, S., Moreadith, R.W. Dev. Dyn. (1996) [Pubmed]
  10. Cloning and functional characterization of a new Ski homolog, Fussel-18, specifically expressed in neuronal tissues. Arndt, S., Poser, I., Schubert, T., Moser, M., Bosserhoff, A.K. Lab. Invest. (2005) [Pubmed]
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