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Gene Review

Dync2li1  -  dynein cytoplasmic 2 light intermediate...

Mus musculus

Synonyms: 4933404O11Rik, CGI-60, Cytoplasmic dynein 2 light intermediate chain 1, D2lic, LIC3, ...
 
 
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High impact information on Dync2li1

  • Cells of the ventral node of mouse embryos lacking mD2LIC have an altered morphology and lack monocilia, and expression of Foxa2 and Shh in this structure is reduced or completely absent [1].

References

  1. Targeted deletion of the novel cytoplasmic dynein mD2LIC disrupts the embryonic organiser, formation of the body axes and specification of ventral cell fates. Rana, A.A., Barbera, J.P., Rodriguez, T.A., Lynch, D., Hirst, E., Smith, J.C., Beddington, R.S. Development (2004) [Pubmed]
 
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