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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Terms

 

Gene Review: 

Trib2  -  tribbles homolog 2 (Drosophila)

Mus musculus

Synonyms: AW319517, TRB-2, TRB2, Tribbles homolog 2
 
 
 
 
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Disease relevance of Trib2

 

High impact information on Trib2

  • Together, our data identify Trib2 as an oncogene that induces AML through a mechanism involving inactivation of C/EBPalpha [1].

References

  1. Tribbles homolog 2 inactivates C/EBPalpha and causes acute myelogenous leukemia. Keeshan, K., He, Y., Wouters, B.J., Shestova, O., Xu, L., Sai, H., Rodriguez, C.G., Maillard, I., Tobias, J.W., Valk, P., Carroll, M., Aster, J.C., Delwel, R., Pear, W.S. Cancer Cell (2006) [Pubmed]
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