Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

Pphln1 - periphilin 1

Mus musculus

Synonyms: 1110063K05Rik, 1600022A19Rik, CR, HSPC206, HSPC232, ...

Huh, J.W. et al.

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Disease relevance of Pphln1

Molecular evolution of the periphilin gene in relation to human endogenous retrovirus m element [1].

High impact information on Pphln1

HERV-M (human endogenous retrovirus M), related to the super family of HERV-K, has a methionine (M) tRNA primer-binding site, and is located within the periphilin gene on human chromosome 12q12 [1].
Also, Alusq/x (variant 4-9) and L1ME4a (mammalian-wide subfamilies of LINE-1) (variant 10) in humans and SINE (short interspersed repetitive element) and RLTR15 (the mouse putative long terminal repeat) (variant 2) in mice could be driving forces in transcript diversification of the periphilin gene during mammalian evolution [1].

References

Molecular evolution of the periphilin gene in relation to human endogenous retrovirus m element. Huh, J.W., Kim, T.H., Yi, J.M., Park, E.S., Kim, W.Y., Sin, H.S., Kim, D.S., Min, D.S., Kim, S.S., Kim, C.B., Hyun, B.H., Kang, S.K., Jung, J.S., Lee, W.H., Takenaka, O., Kim, H.S. J. Mol. Evol. (2006) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

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