Gene Review:
Rapgef3 - Rap guanine nucleotide exchange factor...
Mus musculus
Synonyms:
2310016P22Rik, 9330170P05Rik, EPAC 1, Epac, Epac1, ...
- Simultaneous optical measurements of cytosolic Ca2+ and cAMP in single cells. Harbeck, M.C., Chepurny, O., Nikolaev, V.O., Lohse, M.J., Holz, G.G., Roe, M.W. Sci. STKE (2006)
- Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: effects of silencing CREB gene expression on Akt activation. Misra, U.K., Pizzo, S.V. J. Biol. Chem. (2005)
- Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line. Landa, L.R., Harbeck, M., Kaihara, K., Chepurny, O., Kitiphongspattana, K., Graf, O., Nikolaev, V.O., Lohse, M.J., Holz, G.G., Roe, M.W. J. Biol. Chem. (2005)
- Cutting edge: macrophage inhibition by cyclic AMP (cAMP): differential roles of protein kinase A and exchange protein directly activated by cAMP-1. Aronoff, D.M., Canetti, C., Serezani, C.H., Luo, M., Peters-Golden, M. J. Immunol. (2005)
- Role of the exchange protein directly activated by cyclic adenosine 5'-monophosphate (Epac) pathway in regulating proglucagon gene expression in intestinal endocrine L cells. Lotfi, S., Li, Z., Sun, J., Zuo, Y., Lam, P.P., Kang, Y., Rahimi, M., Islam, D., Wang, P., Gaisano, H.Y., Jin, T. Endocrinology (2006)
- cAMP cascade (PKA, Epac, adenylyl cyclase, Gi, and phosphodiesterases) regulates myelin phagocytosis mediated by complement receptor-3 and scavenger receptor-AI/II in microglia and macrophages. Makranz, C., Cohen, G., Reichert, F., Kodama, T., Rotshenker, S. Glia (2006)
- Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state. Rehmann, H., Das, J., Knipscheer, P., Wittinghofer, A., Bos, J.L. Nature (2006)
- CAMP activates Rap1 in differentiating mouse male germ cells: a new signaling pathway mediated by the cAMP-activated exchange factor Epac? Berruti, G. Cell. Mol. Biol. (Noisy-le-grand) (2003)
- Epac1-mediated Rap1 activation is not required for the production of nitric oxide in BV2, murine microglial cells. Moon, E.Y., Oh, S.Y., Han, G.H., Lee, C.S., Park, S.K. J. Neurosci. Res. (2005)
- Increased expression of interleukin-6 by vasoactive intestinal peptide is associated with regulation of CREB, AP-1 and C/EBP, but not NF-kappaB, in mouse calvarial osteoblasts. Persson, E., Voznesensky, O.S., Huang, Y.F., Lerner, U.H. Bone (2005)