Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

Zfp207 - zinc finger protein 207

Mus musculus

Synonyms: 49 kDa zinc finger protein, 8430401D15Rik, BUB3-interacting and GLEBS motif-containing protein ZNF207, BuGZ, Bugz, ...

Taguchi, E. et al.

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High impact information on Zfp207

Zep: A novel zinc finger protein containing a large proline-rich domain [1].
In addition to the proline-rich domain, Zep has an acidic domain and a serine/threonine-rich domain, all of which are frequently found in many transcription factors [1].
In the day-13 mouse embryo, Zep is strongly expressed in the nervous system, i.e. brain, spinal cord, and dorsal root ganglia, with strong to weak expression observed in other regions [1].
Strong Zep expression is observed in adult thymus, lung, spleen, testis, and ovary [1].
In situ hybridization reveals strong signals for Zep mRNA in the cerebellum and olfactory bulb with moderate signals detected in the hippocampus and cortex [1].

Biological context of Zfp207

Zep contains two C2H2-type zinc finger motifs close to the N-terminal region [1].

Anatomical context of Zfp207

Zep continues to be strongly expressed in the neonatal brain; however, its expression is weak in the brain and spinal cord of adult mice [1].

References

Zep: A novel zinc finger protein containing a large proline-rich domain. Taguchi, E., Muramatsu, H., Fan, Q.W., Kurosawa, N., Sobue, G., Muramatsu, T. J. Biochem. (1998) [Pubmed]

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