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Gene Review

CEP164  -  centrosomal protein 164kDa

Homo sapiens

Synonyms: Centrosomal protein of 164 kDa, Cep164, KIAA1052, NPHP15
 
 
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Other interactions of CEP164

  • The phosphorylation of Ser186 is not affected by RPA knockdown but is severely hampered by MDC1 knockdown. siRNA-mediated silencing of Cep164 significantly reduces DNA damage-induced phosphorylation of RPA, H2AX, MDC1, CHK2, and CHK1, but not NBS1 [1].

References

  1. Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1. Sivasubramaniam, S., Sun, X., Pan, Y.R., Wang, S., Lee, E.Y. Genes Dev. (2008) [Pubmed]
 
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