WikiGenes > Gene > FAN1 (Homo sapiens)http://www.wikigenes.org/e/gene/e/22909.html?wpc=6WikiGenes - Collaborative Publishingen-usCopyright 2026 - WikiGenesSat, 14 Jul 2012 09:19:50 GMTSat, 14 Jul 2012 09:19:50 GMT30Related informationhttp://www.wikigenes.org/e/ref/e/20603015.html#Sun, 6 Nov 2011 08:34:35 GMTMacKay, C. et al.
MRC Protein Phosphorylation Unit, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK

Depletion of FAN1 from human cells causes hypersensitivity to ICLs, defects in ICL repair, and genome instability.
Cell. 2010; 1:65-76

[See paper]]]>Sun, 6 Nov 2011 08:34:35 GMTBiology and medicineRelated informationhttp://www.wikigenes.org/e/ref/e/20671156.html#Sun, 6 Nov 2011 19:44:37 GMTLiu, T. et al.
Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang 310058, China

FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair.
Science. 2010; 5992:693-6

[See paper]]]>Sun, 6 Nov 2011 19:44:37 GMTBiology and medicineRelated informationhttp://www.wikigenes.org/e/ref/e/22611161.html#Sat, 14 Jul 2012 09:19:50 GMTTrujillo, J.P. et al.
Genome Instability and DNA Repair Group, Department of Genetics and Microbiology, Universitat Autònoma de Barcelona, Bellaterra, Spain;

Chromosome fragility was normal in all 4 FAN1-deficient patients, although their cells showed mild sensitivity to mitomycin C in terms of cell survival and G(2) phase arrest, dissimilar in degree to FA cells.
Blood. 2012; 1:86-9

[See paper]]]>Sat, 14 Jul 2012 09:19:50 GMTBiology and medicine