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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Grsf1  -  G-rich RNA sequence binding factor 1

Mus musculus

Synonyms: BB232551, C80280, D5Wsu31e, G-rich sequence factor 1, GRSF-1
 
 
 
 
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High impact information on Grsf1

  • Several potential novel target genes were identified by this means and two, Grsf1 and Fragilis2, were functionally analyzed by RNA interference (RNAi) in completely embryonic stem (ES) cell-derived embryos [1].
  • We show that the gene encoding the RNA-binding factor Grsf1 is important for axial elongation, mid/hindbrain development and axial mesoderm specification, and that Fragilis2, encoding a transmembrane protein, regulates epithelialization of the somites and paraxial mesoderm formation [1].

References

  1. Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos. Lickert, H., Cox, B., Wehrle, C., Taketo, M.M., Kemler, R., Rossant, J. Development (2005) [Pubmed]
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