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Gene Review

Ppfia1  -  protein tyrosine phosphatase, receptor...

Mus musculus

Synonyms: C030014K08Rik, C87158, LIP.1, LIP1, Liprin-alpha1, ...
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High impact information on Ppfia1

  • In this study, we purified the MALS protein complex from brain and found liprin-alpha as a major component [1].
  • Here, we identified and characterized mouse Ppfia1 gene by using bioinformatics [2].
  • Nucleotide sequence of mouse Ppfia1 cDNA was determined in silico by assembling nucleotide sequences of ESTs BY727670, CA327608, BU708520, BQ886535, and a 5'-truncated partial cDNA BC038349 [2].
  • This is the first report on mouse Ppfia1 gene as well as comprehensive comparison of CCND1-EMS1 locus within the human and mouse genomes [2].
  • Ceramide synthase activity of 4Delta.Lass5 cells only utilizes C16 and C18 fatty acids and does not require the help of Lip1p, an essential cofactor of Lag1p/Lac1p [3].

Other interactions of Ppfia1

  • Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex [1].


  1. Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex. Olsen, O., Moore, K.A., Fukata, M., Kazuta, T., Trinidad, J.C., Kauer, F.W., Streuli, M., Misawa, H., Burlingame, A.L., Nicoll, R.A., Bredt, D.S. J. Cell Biol. (2005) [Pubmed]
  2. Identification and characterization of mouse Ppfia1 gene in silico. Katoh, M., Katoh, M. Int. J. Mol. Med. (2003) [Pubmed]
  3. Yeast sphingolipids do not need to contain very long chain fatty acids. Cerantola, V., Vionnet, C., Aebischer, O.F., Jenny, T., Knudsen, J., Conzelmann, A. Biochem. J. (2007) [Pubmed]
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